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Gene expression scope: Pickart and Margolina, using the Broad Institute's Connectivity Map database, reported that GHK-Cu appears to modulate expression of over 4,000 human genes, skewing toward anti-inflammatory, collagen-synthetic, DNA-repair, and anti-apoptotic gene sets

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[ 14 ] BACH1 can also recruit a histone H3K4me1/2 demethylase named lysine‐specific demethylase 2 (LSD2), bind to p53 R175H and form BACH1‐p53 R175H ‐LSD2 complex, which modifies histone methylation status at the promoter of BACH1 targets and subsequently activates the genes transcription

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